Healing Multiple Sclerosis Naturally

Freshly harvested root vegetables and leafy greens

Multiple Sclerosis or MS  is a chronic disease involving the central nervous system and demyelinating. The immune system mistakenly attacks the brain, optic nerves, spinal cord and nerves.

This is the research I did  into how to help myself and thought I would share with everyone.

Make changes that can help treat Multiple sclerosis naturally.

"High prevalence of vitamin A, B12 and D3 deficiency amongst MS patients"

Biotin Multiple Sclerosis

Biotin also is known as vitamin B7 or vitamin H

Food High in Biotin - Brewer's yeast, nuts,  Swiss chard

Research:

Can biotin help treat multiple sclerosis?

High Dose Biotin as Treatment for Progressive Multiple Sclerosis (P3.039)

High doses of biotin in chronic progressive multiple sclerosis: a pilot study.

Biotin Disease Treatment Multiple sclerosis

High dose biotin as treatment for progressive multiple sclerosis.

MD1003 (high-dose biotin) for the treatment of progressive multiple sclerosis: A randomised, double-blind, placebo-controlled study.

Effect of MD1003 in Spinal Progressive Multiple Sclerosis (MS-SPI)

Intersections of pathways involving biotin and iron relative to therapeutic mechanisms for progressive multiple sclerosis.

MD1003 is under study for its potential capacity to promote myelin synthesis, impact disease progression and improve disability in people with primary and secondary progressive MS.

High-dose biotin for Multiple Sclerosis: A Systematic Review and Meta-Analyses of Randomized Controlled Trials

Articles:

High dose biotin withdrawn from European licensing

Can biotin help treat multiple sclerosis?

Using Biotin? It Could Impact Your Lab Results

High-dose Biotin Triples Relapse Rate in Primary-Progressive MS

High-Dose Biotin Leading to Pseudohyperthyroidism in Multiple Sclerosis

Lions Mane Mushroom

Lions Mane Mushroom (Hericium erinaceus)

Other Names: pom pom mushroom, bearded hedgehog mushroom, monkey head mushroom, bearded tooth mushroom, satyr's beard, bearded tooth fungus

medicinal mushroom

Research:

Neurohealth Properties of Hericium erinaceus Mycelia Enriched with Erinacines.

Neuronal Health – Can Culinary and Medicinal Mushrooms Help?

Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia.

Neuroregenerative potential of lion's mane mushroom, Hericium erinaceus (Bull.: Fr.) Pers. (higher Basidiomycetes), in the treatment of peripheral nerve injury (review).

Chemistry, Nutrition, and Health-Promoting Properties of Hericium erinaceus (Lion's Mane) Mushroom Fruiting Bodies and Mycelia and Their Bioactive Compounds.

Vitamin B12[c-lactone], a biologically inactive corrinoid compound, occurs in cultured and dried lion's mane mushroom (Hericium erinaceus) fruiting bodies.

Hericium erinaceus: an edible mushroom with medicinal values.

Nerve growth factor-inducing activity of Hericium erinaceus in 1321N1 human astrocytoma cells.

Lion's Mane, Hericium erinaceus and Tiger Milk, Lignosus rhinocerotis (Higher Basidiomycetes) Medicinal Mushrooms Stimulate Neurite Outgrowth in Dissociated Cells of Brain, Spinal Cord, and Retina: An In Vitro Study.

 

CBD - Cannabinoid Multiple Sclerosis

CBD

The Cannabinoid Use in Progressive Inflammatory brain Disease (CUPID) trial

Vitamins & Minerals

Vitamins and minerals help your body grow, survive, stay healthy and work the way it should.

A review on potential roles of vitamins in incidence, progression, and improvement of multiple sclerosis.

Vitamins, Minerals & Herbs in MS

Vitamin A - Retinol

Vitamin A also known as retinol.

Improving the body's natural defence, growth and development, while maintaining the immune system, and vision.

Research:

Vitamin A and Alzheimer's disease.

Impact of Vitamin A Supplementation on Disease Progression in Patients with Multiple Sclerosis.

Effect of Vitamin A Supplementation on fatigue and depression in Multiple Sclerosis patients: A Double-Blind Placebo-Controlled Clinical Trial.

Nutritional supplementation of vitamin A and health-related outcomes in patients with multiple sclerosis: A protocol for a systematic review and meta-analysis of randomized clinical trials.

Dietary Supplements on Controlling Multiple Sclerosis Symptoms and Relapses: Current Clinical Evidence and Future Perspectives. - "High prevalence of vitamin A, B12 and D3 deficiency amongst MS patients".

Vitamin E

Vitamin E - fat-soluble

Antioxidant and anti-inflammatory properties

Low levels of vitamin E can cause nerve problems.

Foods high in Vitamin E -  sunflower seeds, Almonds,
Peanuts, Beet greens, Spinach, Pumpkin, Red  peppers, Asparagus, Mango and Avocado

Research:

Alpha-tocopherol and MRI Outcomes in Multiple Sclerosis – Association and Prediction

Vitamin D / D3

Vitamin D fat-soluble

Vitamin D2 (ergocalciferol) – synthesized by plants and not produced by the body.
Vitamin D3 (cholecalciferol) – which is produced in the skin when sunlight strikes it.

Combine with vitamin K2 and magnesium.

Beware Calcium Levels when taking high doses. Vitamin D promotes calcium absorption.

The Coimbra Protocol is based around high doses of vitamin D.

Foods -Mushrooms, Soy, almond, and oat milks, vitamin D fortified.

Research:

Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis.

Role of vitamin D in the onset, progression, and severity of multiple sclerosis.

Vitamin D and multiple sclerosis: review of a possible association.

Impact of vitamin D in neurological diseases and neurorehabilitation: from dementia to multiple sclerosis. Part I: the role of vitamin D in the prevention and treatment of multiple sclerosis

Vitamin D-Binding Protein Polymorphisms, 25-Hydroxyvitamin D, Sunshine and Multiple Sclerosis.

MS Sunshine Study: Sun Exposure But Not Vitamin D Is Associated with Multiple Sclerosis Risk in Blacks and Hispanics.

The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health

High-dose vitamin D supplementation reduces IL-17-producing CD4+ T-cells and effector-memory CD4+ T-cells in multiple sclerosis patients

Vitamin K

Vitamin K - fat-soluble

Vitamin K1 - Green leafy vegetables such as lettuce, broccoli, kale, spinach, blueberries and figs.

Vitamin K2 - Abundant in fermented foods

Supplements:
Vitamin K1 - phylloquinone and phytonadione
Vitamin K2 - menaquinone-4, and menaquinone-7 

Research:

Vitamin K2 in multiple sclerosis patients.

Research progress on the anticancer effects of vitamin K2.

Article: How Vitamin K is Good for the Brain and Alzheimer’s Prevention

Article: Vitamin K2 – The new vitamin D in MS?

Vitamin B

Is there a Link between Vitamin B and Multiple Sclerosis?

 

Vitamin B1 - Thiamine

Converts food to energy aids in mental focus and brain function

nutritional yeast, coriander, pine nuts, Jerusalem artichokes, hibiscus tea, watermelon, whole grains,  soymilk, soybeans, rice bran, wheat germ, sunflower seeds, macadamia nuts (or butter), tahini, sesame seeds, spirulina, green peas, most beans, asparagus

High dose thiamine improves fatigue in multiple sclerosis

Vitamin B3 - Niacin

aids in mental focus and brain function

Vitamin B9 - Folate

Merges with Vitamin B12 and Vitamin C to utilize proteins and is essential for healthy brain development

Vitamin B12, folate, and homocysteine levels and multiple sclerosis: A meta-analysis

Folic acid with or without vitamin B12 for cognition and dementia.

Vitamin B6 - pyridoxine

aids in maintaining homeostasis, prevents anxiety by helping the amino acid tryptophan convert to niacin and serotonin for healthy nerve function

Vitamin B12

Vitamin B12, demyelination, remyelination and repair in multiple sclerosis.

Article: Vitamin B12 - Other names: cobalamin, hydroxocobalamin, Cobalin-H

 

Lipoic Acid

Lipoic acid (also known as alpha lipoic acid) is an antioxidant

Foods - lipoic acid in very low amounts. They include spinach, broccoli, yams, potatoes, yeast, tomatoes, Brussels sprouts, carrots, beets, and rice bran.

Lipoic acid in secondary progressive MS

Coenzyme Q10

Coenzyme Q10 - CoQ10 or Ubiquinone is fat-soluble

Antioxidant the body produces naturally.

Coenzyme Q10 supplementation reduces peripheral oxidative stress and inflammation in interferon-β1a-treated multiple sclerosis.

Coenzyme Q10 supplementation reduces oxidative stress and increases antioxidant enzyme activity in patients with relapsing-remitting multiple sclerosis.

Coenzyme Q10 supplementation ameliorates inflammatory markers in patients with multiple sclerosis: a double blind, placebo, controlled randomized clinical trial.

Creatine

nitrogenous organic acid

Energy for muscle contractions.

Creatine Enhances Mitochondrial-Mediated Oligodendrocyte Survival After Demyelinating Injury

Effect of creatine supplementation on muscle capacity in individuals with multiple sclerosis

Chrysin

Neuroprotective effects of chrysin: From chemistry to medicine.

Read our page Chrysin

Luteolin

Luteolin as a potential preventive and therapeutic candidate for Alzheimer's disease.

Luteolin as an anti-inflammatory and neuroprotective agent: A brief review.

Read our page Luteolin

Carotenoids

Molecular Anti-inflammatory Mechanisms of Retinoids and Carotenoids in Alzheimer's Disease

Carotenoids and Alzheimer's disease: an insight into therapeutic role of retinoids in animal models.

Iodine

Iodine - mineral to make thyroid hormones. Thyroid hormones aid proper bone and brain development.

Foods - Seaweed, kelp

Disease family trees: the possible roles of iodine in goitre, cretinism, multiple sclerosis, amyotrophic lateral sclerosis, Alzheimer's and Parkinson's diseases and cancers of the thyroid, nervous system and skin.

The iodine-selenium connection: its possible roles in intelligence, cretinism, sudden infant death syndrome, breast cancer and multiple sclerosis.

Selenium

Selenium - mineral aids cognitive function.

Foods: Brazil Nuts, chai seeds, whole grains, cashews

Found this interesting reading "sugary foods like baked goods and sweetened beverages can actually leach minerals like selenium from the body"

Selenium: What it does and how much you need

Is Selenium Helpful or Harmful in MS? This Antioxidant Has an Ambiguous Role in MS

Selenium in chronic neurologic diseases. Multiple sclerosis and Batten's disease.

Magnesium

Magnesium - mineral. Helps to maintain normal nerve and muscle function. Regulating muscle contractions.

Foods: Almonds, Cashews, Peanuts, Spinach, Black beans, Edamame

Article: Multiple Sclerosis: Magnesium, Selenium, Iodine and Mercury Connection

Research:

Multiple sclerosis: decreased relapse rate through dietary supplementation with calcium, magnesium and vitamin D.

Magnesium concentration in brains from multiple sclerosis patients

Ashwagandha

Ashwagandha 

Ayurveda Medicine - have been suggested to have beneficial effects for MS-associated symptoms, including fatigue, spasticity, anxiety, depression, and pain.

Combinations of Ashwagandha Leaf Extracts Protect Brain-Derived Cells against Oxidative Stress and Induce Differentiation

A Potential Alternative against Neurodegenerative Diseases: Phytodrugs

Omega 3

Omega 3 fatty acids reduce inflammation 

MS sufferers have elevated levels of inflammation.

Food - Chia Seeds, Flaxseeds, Walnuts,

Effect of omega-3 fatty acids and fish oil supplementation on multiple sclerosis: a systematic review.

N-3 PUFAs induce inflammatory tolerance by formation of KEAP1-containing SQSTM1/p62-bodies and activation of NFE2L2

Zinc

Zinc in Multiple Sclerosis: A Systematic Review and Meta-Analysis.

[Zinc concentration in the central nervous system in a case of multiple sclerosis--comparison with other neurological diseases].

Concentrations of zinc and iron in the brains of Guamanian patients with amyotrophic lateral sclerosis and parkinsonism-dementia.

n-acetylglucosamine

n-acetylglucosamine (NAG)  

N-acetylglucosamine May Promote Myelin Repair in Multiple Sclerosis

Simple sugar possible therapy for repairing myelin in multiple sclerosis

N-acetylglucosamine drives myelination by triggering oligodendrocyte precursor cell differentiation

Simple sugar found in human breast milk possible therapy for repairing myelin in multiple sclerosis

Magnolol and honokiol

Magnolia has been used for thousands of years in traditional Chinese and Japanese medicines for their sedative, antibiotic, antitumor, antioxidant, anti-inflammatory, and antispastic effects.

Honokiol is a polyphenol compound lignan.

Honokiol can permeate the blood brain barrier to increase bioavailability in neurological tissues.

Studies have provided some evidence of its ability to be a effective neuroprotective for the central nervous system.

Research has should it could be a promising treatment for neurodegenerative diseases

Research:

Safety and Toxicology of Magnolol and Honokiol

Magnolol and honokiol account for the anti-spasmodic effect of Magnolia officinalis in isolated guinea pig ileum

Neuroprotective effects of honokiol: from chemistry to medicine

Neuro-Modulating Effects of Honokiol: A Review

Pharmacology, Toxicity, Bioavailability, and Formulation of Magnolol: An Update

Inhibition of smooth muscle contraction by magnolol and honokiol in porcine trachea

 

Neuropathic Pain

Nutmeg and St John Wort
Herbal medicinal products or preparations for neuropathic pain
Capsaicin (Pepper)
Topical capsaicin (high concentration) for chronic neuropathic pain in adults.
Cannabis
Cannabis-based medicines for chronic neuropathic pain in adults

Plantbased Diet

Low-fat, plant-based diet have less fatigue.

Article: Multiple sclerosis symptoms improved with fruit and veg

Influence of Diet in Multiple Sclerosis: A Systematic Review.

Article: Multiple sclerosis: Antioxidant may slow disease progression

Multiple Sclerosis and Plant-Based Nutrition 

Sulfur Rich food

Diet & Doctors

Roy Swank Diet - The Multiple Sclerosis Diet Book

Dr. Dean Ornish - Ornish Diet

Dr. John McDougall

T Colin Campbell - Plantbased Dr

Coimbra protocol - High Doses of Vitamin D for autoimmune Diseases

Dr. Terry Wahls Mitochondria Diet

Natural anti-inflammatory

Many people with MS have high inflammation in the body so this section is looking at natural anti-inflammatory.

A Review of Various Antioxidant Compounds and their Potential Utility as Complementary Therapy in Multiple Sclerosis.

Devils Claw - Harpagosides

Devils Claw - harpagosides - Natural anti-inflammatory

rheumatic and arthritic and digestive problems

side effects can reactivate old ulcers, powerful anti-coagulant can cause internal bleeding. Should never used with aspirin, ibuprofen, NSAIDs and anti-coagulants

Harpagoside Content in Devil's Claw Extracts.

Effects of Devil's Claw (Harpagophytum procumbens) on the multidrug transporter ABCB1/P-glycoprotein.

Devil's Claw (Harpagophytum procumbens) as a treatment for osteoarthritis: a review of efficacy and safety.

Curcumin - Turmeric

Curcumin active ingredient of turmeric anti inflammatory properties.

White Willow Bark Extract

Willow bark is the bark of a willow tree (Salix).

Bark contains salicin, a  similar compound to aspirin.

The herbal extract has been a key way to treat relieve pain, inflammation, and fever in traditional herbal medicine.

A systematic review on the effectiveness of willow bark for musculoskeletal pain.

Review of Anti-Inflammatory Herbal Medicines

Ginger

Ginger has anti inflammatory compounds and can help alleviate muscle and joint pain.

Therapeutic potentials of ginger for treatment of Multiple sclerosis: A review with emphasis on its immunomodulatory, anti-inflammatory and anti-oxidative properties.

Boswellia - Frankincense

Boswellia - Frankincense believed to treat chronic inflammatory illnesses

A standardised frankincense extract reduces disease activity in relapsing-remitting multiple sclerosis (the SABA phase IIa trial).

Camphor

Camphor can help to relieve muscle cramps, spasms, and stiffness.

Camphor has naturally antispasmodic and relaxant properties.

Antispasmodic activity of extracts and compounds of Acalypha phleoides Cav.†

Clove

Clove has been reported as a analgesic since the 13th century and  soothe muscle aches, pains and antispasmodic.

Clove (Syzygium aromaticum): a precious spice

Syzygium aromaticum L. (Myrtaceae): Traditional Uses, Bioactive Chemical Constituents, Pharmacological and Toxicological Activities

Threonine

Threonine is an essential amino acid. "Essential" amino acids are not made in the body so must be obtained from food in our diet.

Foods: Soy, nuts, seeds, beans, and lentils.

Potentially useful in muscle tightness (spasticity)

An antispasticity effect of threonine in multiple sclerosis

L-Threonine Administration in Multiple Sclerosis

Nutrition & Multiple Sclerosis

Reduce inflammation by increasing natural antioxidants and polyphenols using the power of the protective compounds found in plants.

Coffee contains polyphenols and other anti-inflammatory compounds.

Anti-inflammatory diet high in fruits, vegetables, nuts, whole grains, and healthy oils.

Inflammatory Foods to Avoid: Gluten, Sugar, Dairy, processed foods, refined carbohydrates (breads), red meats, 

Anti-inflammatory foods: Tomatoes, nuts (almonds, walnuts), green leafy vegetables (spinach, kale), strawberries, blueberries, cherries, and oranges

Nutrition Facts in Multiple Sclerosis

The molecular basis of nutritional intervention in multiple sclerosis: a narrative review.

Nutrition facts in multiple sclerosis.

Diet, Gut Microbiota, and Vitamins D + A in Multiple Sclerosis.

Dopamine, T cells and multiple sclerosis (MS).

Is there a link between vitamin B and multiple sclerosis?

Latitude, Vitamin D, Melatonin, and Gut Microbiota Act in Concert to Initiate Multiple Sclerosis: A New Mechanistic Pathway.

Intermittent Fasting

Intermittent Fasting 

Can Intermittent Fasting Help MS?

Intermittent calorie restriction alters T cell subsets and metabolic markers in people with multiple sclerosis

Can fasting improve MS symptoms?

Intermittent Fasting in MS Leads to Immune Cell, Metabolic Changes

Fasting and MS

Diet mimicking fasting promotes regeneration and reduces autoimmunity and multiple sclerosis symptoms

Fasting-like Diet Reduces Multiple Sclerosis Symptoms

Fasting-like diet reduces multiple sclerosis symptoms

MS Bloggers

Bloggers:

Dinosaurs, Donkeys and MS

Tripping On Air

My new Normals

Books Overcoming MS

Books:

Multiple Sclerosis and (lots of) Vitamin D: My Eight-Year Treatment with The Coimbra Protocol for Autoimmune Diseases - Ana Claudia Domene

Overcoming Multiple Sclerosis: The Evidence-based 7 Step Recovery Program - George Jelinek

Wahls Protocol, The : A Radical New Way to Treat All Chronic Autoimmune Conditions Using Paleo Principles - Terry L. Wahls, M.D.

Older Addition - Overcoming Multiple Sclerosis: An Evidence-Based Guide to Recovery - George Jelinek

Articles:

Natural Remedy Dos and Don’ts for Multiple Sclerosis

Additional Research

SerpinB1 controls encephalitogenic T helper cells in neuroinflammation
Targeting a rogue T cell prevents and reverses multiple sclerosis in mice

Potential causes of MS

Recent study shows strong connection between MS and Epstein-Barr virus - The study analyzed blood samples taken from 10 million current and former  U.S. servicemen and -women.

Epstein-Barr virus may be leading cause of multiple sclerosis

Epstein-Barr Virus Implicated as Cause of Multiple Sclerosis

Multiple Sclerosis Is Likely Caused by a Virus, Finds Study of 10 Million Military Personnel

Epstein-Barr Virus May Be Leading Cause of Multiple Sclerosis

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