Phytonutrients and phytochemicals: a practical guide to plant foods

Basket of root vegetables and leafy greens

The red of a tomato, the purple of a berry and some of the compounds in a cup of tea are examples of the chemistry that makes plant foods interesting. Phytochemicals are compounds produced by plants. You may also see them called phytonutrients, especially when people discuss their possible effects on health. [1] [2] [3]

You do not need to remember their names to include them in your food. A varied plant-based diet brings many compounds together. Evidence is stronger for the foods and overall diet than for the benefits of isolated phytochemicals. [1]

This is a part of food I enjoy thinking about: what else could go into a salad, which vegetables would work in a soup, or how to use something different from the shopping basket. I would begin with that curiosity and the meals you already like.

What is the difference between phytochemicals and phytonutrients?

The terms overlap in everyday nutrition writing. Phytochemical describes a chemical made by a plant; phytonutrient is often used to emphasise a possible nutritional or health role. The Linus Pauling Institute defines phytochemicals, in the broadest sense, as:

“chemicals produced by plants”

Linus Pauling Institute, Oregon State University [1]

In health research, the term generally refers to plant compounds beyond essential nutrients. They should not all be treated like vitamins with established daily requirements. [1] There are exceptions to a neat dividing line: some carotenoids, including beta-carotene, can be converted into vitamin A by your body. [3]

If a name sounds complicated, look for the food it belongs to. Learning that an apple contains flavonoids can be interesting. You can still enjoy the apple without learning the chemistry first.

Which plant foods contain phytochemicals?

They occur across plant foods, including fruit, vegetables, pulses, whole grains, nuts and tea. [1] The compounds fall into overlapping families. Flavonoids are part of the larger polyphenol group; anthocyanins and isoflavones sit within the flavonoid family. [2]

There are many more types to explore than a short list can show. Some names describe a broad family and others a single compound inside it. The explanations include established roles in plants, biological actions studied in people, and promising laboratory findings. These are different kinds of evidence.

Broad families

Phytochemical families and what makes them interesting
Group or compoundWhere it comes fromWhat it does, or what research is exploring
PolyphenolsFruit, vegetables, tea, cocoa and other plant foodsA broad family containing flavonoids and compounds such as resveratrol. Researchers study their effects on cell signalling and other processes; there is no single effect shared equally by every polyphenol. [2] [18]
Flavonoids and bioflavonoidsApples, onions, citrus fruit and teaBioflavonoids is another name commonly used for flavonoids. In plants, members of this family help with pigmentation and responses to environmental stresses. Human research examines signalling and vascular effects. [2]
Anthocyanins and anthocyanidinsRed, blue and purple berries and grapesContribute red, blue and purple pigments. Anthocyanins are sugar-linked forms of anthocyanidins. Their biological actions are being studied; colour alone does not establish a health benefit. [2]
ProanthocyanidinsApples, berries, cocoa and grape seedsLinked chains of flavonoid units. Grape-seed extracts have been studied for blood pressure and cholesterol, with small, varied trials. Those findings cannot simply be assigned to every food containing them. [2] [25]
CarotenoidsCarrots, tomatoes, spinach and kalePlant pigments including beta-carotene, lycopene and lutein. Some can supply vitamin A after conversion; others cannot. Lutein and zeaxanthin are present in the retina of the eye. [3]
GlucosinolatesBroccoli, cabbage, kale and Brussels sproutsBreak down into compounds including isothiocyanates. These are studied for effects on enzymes and cellular responses to stress. Food studies and laboratory mechanisms do not establish cancer treatment. [4]
Allium compounds, including organosulfur compounds and sulfidesGarlic and related allium vegetablesCrushing garlic allows enzymes to turn alliin into allicin, which can form other sulfur compounds. Research on garlic preparations includes cardiovascular risk factors, with results depending on the preparation. [12]
Phytoestrogens, including isoflavonesSoya foods; lignan-containing foods such as flaxseedSome compounds or their metabolites can interact with estrogen receptors. Their effects depend on the compound and tissue; describing them as universal hormone balancers would be misleading. [14] [13]

Individual compounds and food-based topics

Compounds to explore in more detail
Group or compoundWhere it comes fromWhat it does, or what research is exploring
LignansFlaxseed, sesame seeds, whole grains and other plantsGut bacteria can convert plant lignans into enterolignans, which have weak estrogenic activity. The contribution of lignans themselves to disease prevention is still being investigated. [13]
SulforaphaneFormed from glucoraphanin in broccoli and some other cruciferous vegetablesAn isothiocyanate studied for effects on enzymes involved in handling foreign chemicals and cellular stress. This is more specific than saying broccoli flushes out toxins. [4]
ChlorophyllGreen leaves and algaeThe green pigment captures light for photosynthesis. Chlorophyll supplements and chlorophyllin are different products; the plant role does not establish a general human detox effect. [15]
CurcuminTurmericA yellow pigment studied for inflammatory pathways. Early human evidence on some turmeric/curcumin products and knee-osteoarthritis symptoms is encouraging, but stronger evidence is needed. Culinary turmeric is not the same as a tested extract. [16]
Ellagic acidRaspberries, strawberries, pomegranates and walnutsShows antioxidant and other biological activity in laboratory work. It is an interesting research topic, but there is no evidence supporting its use as a cancer treatment. [17]
ResveratrolGrape skins, peanuts and some berriesStudied for cell signalling, stress responses and ageing mechanisms. Laboratory and animal lifespan findings do not demonstrate that supplements make humans live longer. [18]
CapsaicinChilli peppersResponsible for chilli heat. Topical capsaicin medicines act on pain-related nerve cells and can relieve some muscle and joint pain. Eating chilli is not equivalent to applying a medicine. [19]
AstaxanthinCertain microalgae, including Haematococcus pluvialisA pink-red carotenoid pigment. Included here because algal pigments are often discussed alongside plant compounds. EFSA has assessed supplement safety; that assessment does not establish a general health benefit. [20]
PhytosterolsNuts, seeds, grains and other plant foods; some enriched foodsPlant sterols and stanols reduce intestinal cholesterol absorption. LDL reduction is best established for suitable enriched products at studied amounts, rather than an unspecified serving of any plant food. [26]

Plant extracts and specialist research topics

These were part of my wider list too. They offer further things to learn about, although they are not all everyday food ingredients or reasons to buy a supplement.

Specialist compounds and their research context
Group or compoundWhere it comes fromWhat it does, or what research is exploring
Boswellic acidsBoswellia resin, also known as frankincensePreclinical work examines enzymes involved in inflammation. Small studies of Boswellia extracts suggest possible help with osteoarthritis symptoms, but the evidence needs better trials. Resin extracts are different from ordinary foods. [22] [21]
CoumarinsA family including coumarin, found in Cassia cinnamon and other plantsCoumarin contributes fragrance and flavour. It is not a nutrient to maximise: substantial ongoing exposure can harm the liver in susceptible people. Ceylon cinnamon generally contains much less coumarin than Cassia. [23]
DithiolethionesNaturally occurring and synthetic compounds discussed in specialist researchStudied for increasing the activity of phase 2 enzymes, which help process foreign chemicals. Much work concerns experimental agents and animal models; this is not an established dietary treatment. [24]

Antioxidants describe an activity rather than a separate phytochemical family. The section below explains that distinction; the antioxidants and free radicals article is another route into the topic.

Some linked guides are older and still await the same evidence review as this overview. The sources beside each summary above support the explanation given here.

Is eating the rainbow useful?

Colour can be a helpful reminder to vary your fruit and vegetables. Some plant pigments, such as anthocyanins and carotenoids, contribute to those colours. Green leaves can contain carotenoids too, even when their yellow or orange pigments are less obvious. [2] [3]

It is a prompt, rather than a score for how healthy your dinner is. Pale foods have a place: onions contain flavonoids, and whole grains and beans belong in a varied plant-focused diet. [2] [10] A plate does not need every colour at every meal.

I would think across the week. If your usual soup has carrots, perhaps add another vegetable you enjoy. If breakfast is always the same fruit, try a different one when it suits your budget. Familiar favourites can stay while you explore.

What does research actually tell us?

A 2017 systematic review by Aune and colleagues brought together 95 prospective studies, which followed people over time. Higher fruit and vegetable intake was associated with lower risks of cardiovascular disease and death from any cause; the association with total cancer was smaller. [5]

These were observational findings. They cannot establish that one phytochemical caused the difference, and other habits or imperfect dietary reporting may affect the results. They support interest in fruit and vegetables as foods, rather than prove that a capsule containing one of their compounds will have the same effect. [5]

What is a dietary phytochemical index?

Researchers have also explored ways to estimate how much of a person's diet comes from phytochemical-rich foods. In a small study published in 2010, Vincent and colleagues used a dietary phytochemical index based on the proportion of food energy coming from those foods. Among 54 young adults, the index was related to measures of body fat and oxidative stress, but not to the cytokines measured, which are immune-signalling proteins. [27]

This was a cross-sectional study, meaning it compared diet and health measures without assigning people a diet to follow. It cannot show that phytochemicals caused the differences or give you a daily amount to aim for. I find the food question more useful in the kitchen: could you add beans to your soup, another vegetable to dinner or some berries to breakfast? [27]

Where does cancer-prevention advice fit?

The World Cancer Research Fund recommends making whole grains, vegetables, fruit and pulses a major part of the usual diet. Its evidence review identifies strong evidence for whole grains and foods containing fibre reducing colorectal cancer risk. Evidence varies for other food and cancer combinations. [10]

Reducing risk is different from guaranteeing prevention or treating an existing illness. A particular vegetable cannot be promised to prevent cancer, and a laboratory result showing an effect on cancer cells does not establish that eating that food treats cancer in a person. [4] [6]

A plant-based perspective from Dr Michael Greger

NutritionFacts.org, Dr Greger's educational organisation, discusses phytonutrients through everyday foods and makes the point:

“the whole is often greater than the sum of its parts”

NutritionFacts.org, Phytonutrients [7]

I would use that as a reminder to look at the whole food, then check the evidence behind a specific health claim. The topic page introduces research questions; it is not itself a clinical trial. The studies and evidence reviews linked here help distinguish promising ideas from demonstrated outcomes.

Are all phytochemicals antioxidants?

No. Antioxidant describes an activity, rather than one family of plant compounds. Antioxidants interact with free radicals, reactive chemicals that can damage cells. Some phytochemicals show antioxidant activity, while researchers also study other actions, including effects on cell signalling. [6] [2]

Activity measured in a test tube does not tell you how much of a compound reaches tissues after digestion or whether it prevents disease. Flavonoids, for example, are changed during absorption and metabolism, so the substances circulating in your body may differ from those originally in the food. [2]

I would avoid choosing a food simply because its packaging advertises a very high antioxidant score. It is more useful to ask whether you enjoy it, how it fits into your meals and what evidence supports the claim being made.

Does cooking destroy phytochemicals?

Cooking can change them in different ways. It is too simple to say raw is always better. In a laboratory study, Dewanto and colleagues heated tomatoes and found increased bioaccessible lycopene and measured antioxidant activity, while vitamin C decreased. Bioaccessible means available to be released from the food during digestion. [8]

This was a food-analysis study, not a trial showing that cooked tomatoes prevent disease. The practical lesson is that cooking can involve trade-offs, rather than removing all nutritional value. [8] A tomato sauce can have a place alongside a fresh tomato salad.

I would choose a mixture of preparations you enjoy. A warm vegetable soup in winter and a colourful salad in summer can both fit. Follow safe preparation instructions, and do not let worry about the perfect method stop you using the ingredients you have.

How can I include more variety without making cooking difficult?

Start with a meal you already make. You could add beans and another vegetable to a soup, serve a curry with different vegetables, or put a handful of berries over porridge. These are food ideas to adapt, rather than recipes with calculated amounts of phytochemicals.

Planning helps me turn an idea into dinner. Choose an ingredient, decide which meal it will go into and add it to the shopping list. If you buy a cabbage, plan where the rest might go as well, perhaps into soup or another cooked dish.

Keep enough substantial food in the meal too. Variety is one part of eating well; energy, protein and essential nutrients still need attention. The balanced plant-based diet guide explains how to bring those needs together.

Do I need phytochemical supplements or greens powders?

A concentrated extract should not be assumed to reproduce the benefits of the food it came from. Antioxidant supplement trials have not consistently shown cancer-prevention benefits, and some have found harm. [6]

For example, the ATBC randomised trial followed 29,133 male smokers aged 50 to 69 in Finland. Participants receiving beta-carotene supplements had a higher incidence of lung cancer than those not receiving beta-carotene. This was a supplement study in a specific population, not evidence that eating carrots causes the same harm. [11]

If a powder claims to replace vegetables, ask what was actually tested: that product, that dose and a meaningful health outcome, or simply an ingredient in a laboratory? If you take medicines or are receiving cancer treatment, discuss concentrated supplements with your healthcare team before using them. [6]

This is separate from using a supplement for an identified nutrient need. The B12 guide covers reliable B12 sources on a fully plant-based diet. Choosing food for its phytochemicals does not replace that planning.

Does everything need to be fresh or organic?

No. Frozen and tinned fruit and vegetables can count towards your five a day, as can vegetables cooked into meals. Choose tinned options in water or natural juice, without added sugar or salt where available. [9] You do not need a basket of fresh produce every day to make a useful change.

I personally choose organic when it suits me, but I would not want the cost to put you off eating more plants. Use what you can afford and will enjoy cooking. A few dependable cupboard and freezer ingredients may make more sense for your week than lots of unfamiliar fresh food.

A few more practical questions

Do I need to calculate a daily phytochemical target?

There is no single daily target that covers this whole collection of compounds. The category includes many substances with different properties. [1] Focus on a varied diet and practical food guidance, rather than trying to add up an undefined total.

Does a superfood provide everything?

I would keep your choices broad. No single ingredient has to carry the whole diet, and you do not need expensive powders to try another vegetable, pulse or whole grain. Choose one addition you would enjoy this week and give it a place in a meal.

Resources

Research and guidance cited on this page.

  1. Linus Pauling Institute: Phytochemicals

    University reference on terminology and the limits of attributing the benefits of complex foods to individual compounds. No universal phytochemical requirement is established.

  2. Linus Pauling Institute: Flavonoids

    University evidence review and food-source table. Explains flavonoid families, anthocyanins, isoflavones, digestion and metabolism. Food examples do not establish a therapeutic dose.

  3. Linus Pauling Institute: Carotenoids

    Food sources, pigmentation and the distinction between vitamin A precursors and other carotenoids. This article does not promise eye-health or anti-ageing effects.

  4. Linus Pauling Institute: Isothiocyanates

    Explains glucosinolate breakdown, cruciferous food sources and mechanistic research. Cell and animal findings do not establish a cancer treatment in humans.

  5. Aune et al. (2017): Fruit, vegetables and long-term health outcomes

    Indexed published abstract checked. Meta-analysis of 95 prospective studies. Associations differ by outcome and cannot isolate the effects of individual phytochemicals or establish causation.

  6. National Cancer Institute: Antioxidants and cancer prevention

    Definitions and human supplement trial evidence, including absent benefits or harms in some trials, and the need for advice during cancer treatment.

  7. NutritionFacts.org: Phytonutrients

    Dr Michael Greger's organisation provides a plant-based educational perspective on whole foods. Its broad introductory claims are not treated as clinical proof; specific findings are checked against research.

  8. Dewanto et al. (2002): Thermal processing of tomatoes

    Published abstract checked. Laboratory food study measuring lycopene accessibility, antioxidant activity and vitamin C after heating. It did not measure disease prevention in people.

  9. NHS: Five a day, what counts?

    UK practical guidance including frozen, tinned and cooked produce. Counting towards five a day does not imply identical phytochemical amounts across foods.

  10. World Cancer Research Fund: Whole grains, vegetables, fruit and beans

    Evidence-based food-pattern recommendation. Evidence strength varies by cancer and food group; risk reduction is not a guarantee or treatment claim.

  11. ATBC Study Group (1994): Beta-carotene trial in male smokers

    Published abstract checked. Randomised trial in 29,133 male smokers, followed for five to eight years. Supplement findings should not be extrapolated to ordinary food intake.

  12. Linus Pauling Institute: Garlic and organosulfur compounds

    University review on alliin, allicin formation and research on garlic preparations. Effects of extracts cannot be assumed for an ordinary food serving.

  13. Linus Pauling Institute: Lignans

    Sources, gut microbial conversion and weak estrogenic activity of enterolignans. Clinical disease-prevention roles remain uncertain.

  14. Linus Pauling Institute: Soy isoflavones

    Explains estrogen-receptor interactions and the distinction between food, metabolites and concentrated supplements. This is not a claim that phytoestrogens balance hormones.

  15. Linus Pauling Institute: Chlorophyll and related derivatives

    Plant pigment and photosynthesis; distinguishes natural chlorophyll from semi-synthetic chlorophyllin. General detox claims are not established.

  16. NCCIH: Turmeric and curcumin

    Human evidence and safety summary. Early knee-osteoarthritis findings need better evidence; supplement formulations differ from culinary turmeric.

  17. Memorial Sloan Kettering: Ellagic acid

    Clinical institution summary of food sources and laboratory findings, with no evidence supporting ellagic acid as a cancer treatment.

  18. Linus Pauling Institute: Resveratrol

    Food sources, signalling and ageing research. Animal and laboratory findings do not demonstrate longer human lifespan.

  19. MedlinePlus: Topical capsaicin

    Drug reference describing chilli-derived capsaicin and its effects on pain-related nerve cells in the skin. Topical medicines are not equivalent to eating chillies.

  20. EFSA (2020): Astaxanthin in food supplements

    Safety assessment identifies the pink pigment from Haematococcus pluvialis microalgae. Safety assessment does not establish therapeutic effectiveness or a need to supplement.

  21. NCCIH: Boswellia

    Summary of small, often low-quality studies. Possible osteoarthritis benefits need larger, better trials. This is an herbal extract topic, not an everyday food recommendation.

  22. Memorial Sloan Kettering: Boswellia and boswellic acids

    Identifies boswellic acids in resin and explains preclinical inflammatory-enzyme findings. Mechanisms are distinguished from clinical outcomes.

  23. German Federal Institute for Risk Assessment: Coumarin

    Natural fragrance and flavouring compound in Cassia cinnamon and other plants. Addresses liver risks and lower coumarin levels in Ceylon cinnamon. No disease-treatment claim is made.

  24. Mechanistic review (2001): Phase 2 enzymes and dithiolethiones

    Indexed published abstract checked. Mechanistic review discussing experimental agents such as oltipraz and enzymes involved in processing carcinogens. It does not establish dietary disease prevention.

  25. NCCIH: Grape seed extract and proanthocyanidins

    Summary of small, varied human studies on blood lipids and blood pressure. Extract results do not establish identical effects from ordinary foods.

  26. Linus Pauling Institute: Phytosterols

    Plant sterol/stanol chemistry, reduced intestinal cholesterol absorption and LDL effects of enriched products. Typical food amounts are not equivalent to studied enriched-product doses.

  27. Vincent et al. (2010): Dietary phytochemical index in young adults

    Published abstract checked. Published online in 2009 and in a 2010 journal issue. Small cross-sectional study of 54 adults aged 18 to 30, exploring a food-based index, body fat and oxidative-stress markers. It cannot establish causation or a supplement benefit; cytokine levels were not correlated with the index.

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